乳酸鈉注射液的制造与一般針剂相同,惟有二个特出的問題,茲將我厂長期生产的經驗介紹如下: 乳酸鈉注射液的pH有时表現得極不稳定,調配好的溶液测得pH为7.0,經过灭菌后pH下降極为显著,甚至超出規定限度而造成整批产品不合格。原因是乳酸中常存在一定数量的乳酸酐 The manufacture of sodium lactate injection and the general injection of the same, only two outstanding problems, I will plant long-term production experience is as follows: Sodium lactate injection sometimes showed extremely unstable pH, the deployment of a good solution measured pH 7.0, pH drop after sterilization is extremely significant, even beyond the limits caused by the entire batch of products failed. The reason is that there is often a certain amount of lactate in lactic acid