新生血管的形成是许多眼底疾病的一个重要环节，是致盲的常见原因．但在临床上尚无满意的治疗措施．人们发现：在眼底新生血管周围，往往有视网膜色素上皮细胞（RPE）的存在，而且当增生的RPE包裹新生血管时，新生血管便停止．[1]但RPE对于新生血管的确切作用仍不清楚，有的研 The formation of neovascularization is an important part of many retinal diseases and is a common cause of blindness. However, there is no satisfactory clinical treatment. It has been found that retinal pigment epithelial cells (RPE) are often present around retinal neovascularization, and neovascularization stops when proliferating RPE encases neovascularization. [1] However, the exact role of RPE in neovascularization remains unclear, and some studies