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以大分子为载体的靶向药物在体内的处置，对于其药效的发挥是很重要的。本综述经对文献的分析，与大分子载体的一般药代动力学特点相比较，归纳出以大分子为载体的靶向药物的特点。结果表明：其体内药代性质可用清除率理论来分析。糖受体—糖基化大分子及抗体—抗原的相互作用，也可用具有饱和过程的药代模型来分析。另外，有许多因素可影响靶向药物的药代动力学性质
Targeting drugs targeting macromolecules in the body are important for their efficacy. In this review, we compare the general pharmacokinetic characteristics of macromolecule carriers with the analysis of the literature, and summarize the characteristics of targeted drugs with macromolecules as carrier. The results show that: its pharmacokinetics in vivo clearance rate theory can be used to analyze. The interaction of sugar receptor-glycosylated macromolecules with antibody-antigen can also be analyzed by a pharmacokinetic model with a saturation process. In addition, there are many factors that can affect the pharmacokinetic properties of the targeted drug