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目的评价经皮球囊扩张椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩性骨折的临床效果。方法选取行PKP治疗的骨质疏松性椎体骨折患者68例(95个椎体),回顾性分析患者的临床资料。比较手术前后VAS疼痛评分、SF-36生活质量评分,观察椎体恢复高度、椎体后凸角度(Cobb角)以及并发症发生情况。结果 68例患者均行PKP,骨水泥注入量(4.5±1.3)ml。术后6个月,患者VAS疼痛评分降低,SF-36评分提高;影像学测量显示椎体Cobb角减少,椎体前缘丢失高度恢复的百分比提高;与术前比较,差异有统计学意义(P<0.05)。发生骨水泥渗漏5例;术后2个月内发生相邻节段单椎体骨折2例。结论 PKP治疗椎体压缩性骨折安全、有效,可提高机体功能,减少疼痛,部分纠正后凸畸形。
Objective To evaluate the clinical effect of percutaneous balloon kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fractures. Methods Sixty-eight patients (95 vertebrae) with osteoporotic vertebral fractures treated by PKP were selected. The clinical data of the patients were retrospectively analyzed. VAS pain score, SF-36 quality of life score, height of vertebral body restoration, angle of kyphosis (Cobb angle) and complication were compared before and after operation. Results All the 68 patients underwent PKP and the amount of cement injection was (4.5 ± 1.3) ml. VAS pain scores decreased and SF-36 score increased at 6 months postoperatively. Imaging studies showed that the percentage of vertebral body Cobb angle decreased and vertebral body anterior height loss increased significantly compared with that before operation. The difference was statistically significant P <0.05). 5 cases of leakage of cement occurred; 2 months after the occurrence of adjacent segments of single vertebral fractures in 2 cases. Conclusions PKP is safe and effective in the treatment of vertebral compression fractures. It can improve the body function, reduce pain and partially correct kyphosis.