日本和歌山县立医科大学的井上德浩以SD雄性大鼠为实验对象,应用递增法反复经皮下给予吗啡(20～80mg/kg)后,再经皮下给予甲基苯丙胺(0.5mg/kg)时发现大鼠运动量增加,这种作用随着时间的推移而逐渐消失。在探讨当归芍药散对这种甲基苯丙胺作用的影响时发现,该方(0.05～1.0g/kg,口饲14d)对首次用吗啡的 Inoue Deho, of Wakayama Prefectural Medical University in Japan, used a male SD rat as an experimental subject, and repeated the subcutaneous administration of morphine (20 to 80 mg/kg) followed by subcutaneous administration of methamphetamine (0.5 mg/kg) by an incremental method. It was found that the amount of exercise in rats increased and this effect gradually disappeared over time. When discussing the effect of Danggui Shaoyao San on the effect of this methamphetamine, it was found that this side (0.05-1.0 g/kg, 14 days for oral feeding) was the first to use morphine.