患儿。男,七个月,慢性腹泻2个月。家长给予鸦片约300 mg口服(黄豆粒大小).10 min后,患儿出现呼吸急促,两眼直视、惊厥、昏迷30 min而急诊入院。既往足月剖宫产。查:T:36.3℃,P:160次/min,R:40次/min,体重7kg。发育正常,神志不清,呼吸浅表,压眶反射消失。双瞳缩小如针尖大,光反射(直、间接)消失。颈软,呼吸节律不规整。两肺可闻及哮喘音,心律齐快,160次/min,无杂音,腹(-)。手足湿冷,甲床紫绀,膝反射消失,病理反射(-)。入院后,洗胃未成功,给持续低流量吸氧,可拉明0.375,肌注,50％G.S 20 ml、西地兰0.14 mg缓慢静推,呼吸无改善,心率降为 Children. Male, seven months, chronic diarrhea 2 months. Parents were given opium about 300 mg orally (soybean size) .10 min later, children with shortness of breath, two eyes, convulsions, coma 30 min and emergency admission. Past full-term cesarean section. Check: T: 36.3 ℃, P: 160 times / min, R: 40 times / min, weight 7kg. Normal development, confusion, shallow breathing, pressure orbital reflex disappears. Double-pupil narrowing, such as needle tip, light reflection (straight, indirect) disappear. Soft neck, irregular breathing rhythm. Two lungs can be heard and asthma tone, heart rate Qi fast, 160 beats / min, no noise, abdomen (-). Cold hands and feet, nail bed cyanosis, knee reflex disappeared, pathological reflex (-). After admission, gastric lavage was unsuccessful, continuous low-flow oxygen inhalation, 0.375 mg of Lamine, intramuscular injection of 50% G.S 20 ml, cedilanid 0.14 mg slow static push, no improvement in breathing, reduced heart rate