目的　探讨经食管床食管胃左颈部吻合术治疗食管癌的临床效果。方法　对634 例食管癌患者经食管床行食管胃左颈部吻合术。结果　全组病例术后死亡1 例,颈部吻合口瘘1 例,乳糜胸5 例,4 例行开胸治疗痊愈;肺不张3例,经纤维支气管镜吸痰痊愈;左侧喉返神经损伤3例。结论　本术式可以降低保留食管再发癌的机率。由于吻合口位于颈部,一旦术后出现吻合口瘘,不会污染胸腔,且处理方便,不会对病人造成大的危害。 Objective To investigate the clinical effect of transesophageal and gastric left-neck anastomosis in the treatment of esophageal cancer. Methods A total of 634 patients with esophageal cancer underwent esophageal-gastric left-neck anastomosis through the esophageal bed. Results All patients died in 1 case, anastomotic fistula in 1 case, chylothorax in 5 cases and thoracotomy in 4 cases. Atelectasis in 3 cases was cured by fiberoptic bronchoscopy; the left recurrent laryngeal nerve 3 cases of injury. Conclusion This procedure can reduce the risk of recurrent esophageal cancer. As the anastomosis is located in the neck, once the anastomotic fistula after surgery, does not contaminate the chest, and easy to handle, will not cause great harm to the patient.