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目的了解内蒙古自治区健康人群风疹抗体水平,掌握易感人群的分布特点,为制定预防控制措施提供科学依据。方法将健康人群分为8个年龄组,每组随机抽取不少于30人,应用酶联免疫吸附试验(ELISA)检测风疹IgG抗体。结果采集血清标本754人份,风疹抗体IgG阳性536人份,阳性率71.09%。赤峰市松山区的抗体阳性率和平均抗体浓度(GMC)均最高,分别为80%和28.66 m U/ml;锡林郭勒盟西乌珠穆沁旗为最低,分别为63.16%和17.89 m U/ml。≥20岁组人群抗体阳性率和GMC最高,分别为93.26%和48.16 m U/ml;5~7岁组最低,分别为56.52%和12.78 m U/ml。结论内蒙古自治区不同地区人群风疹免疫水平不同,GMC较低,尤其应加强<1岁和5~7岁组人群的免疫接种。
Objective To understand the level of rubella antibody in healthy population in Inner Mongolia Autonomous Region and to grasp the distribution characteristics of susceptible population and provide a scientific basis for making prevention and control measures. Methods The healthy population was divided into 8 age groups, each group of no less than 30 randomly selected, the enzyme-linked immunosorbent assay (ELISA) detection rubella IgG antibody. Results A total of 754 serum samples were collected, 536 were positive for rubella antibody IgG, the positive rate was 71.09%. The antibody positive rate and the average antibody concentration (GMC) in Songshan District of Chifeng City were the highest, which were 80% and 28.66 mU / ml, respectively. The West Wujumuqin Banner in Xilin Gol League was the lowest with 63.16% and 17.89 mU / ml . The antibody positive rate and GMC of the population aged ≥ 20 years were the highest (93.26% and 48.16 mU / ml, respectively), while the lowest was 56.52% and 12.78 mU / ml in the range of 5-7 years. Conclusion The immunization level of rubella in different areas of Inner Mongolia Autonomous Region is different, and the GMC is lower. In particular, immunization should be strengthened in the crowd <1 year old and 5 ~ 7 years old.