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整合素与配体结合的特征决定细胞游走速度高等动物细胞在组织中的游走主要由细胞表面的粘附受体如整合素(integrins)介导。整合素的作用包括:将细胞与胞外基质配体连结,传递作用力和细胞运动的必须信号。细胞在特定基质中是否能游走及游走速度取决于整合素与...
Characteristics of Integrins and Ligand Binding Determine Higher Traveling Speed of Cells The migration of animal cells in tissues is mainly mediated by cell surface adhesion receptors such as integrins. The role of integrins includes: linking cells to extracellular matrix ligands, transmitting the necessary signals of force and cell motility. Whether cells in a particular matrix can walk and swim depends on the speed of integrins and ...