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恩丹西酮治疗抗癌药物顺铂引起的恶心、呕吐反应５０例，分两组观察。单用组：注射用顺铂前２０ｍｉｎ、后４ｈ各静注恩丹西酮８ｍｇ。联用组：注射用顺铂前４０ｍｉｎ静注地塞米松１０ｍｇ，前２０ｍｉｎ静注恩丹西酮８ｍｇ。两组停用顺铂后均改为口服恩丹西酮４ｍｇ，１日２次，连用２天。单用组对恶心呕吐控制率分别为８８％、９２％。２～５ｄ为７６％～９２％。联用组对恶心呕吐控制率分别为９２％、９６％。２～５ｄ为８０％～９６％。两组之间无统计学差异（Ｐ＞００５）。结果表明恩丹西酮疗效确切，联用组药量减半疗效不变。
Ondansetron treatment of cancer drugs cisplatin caused by nausea and vomiting in 50 cases, divided into two groups. Single-use group: Ondansetron 8 mg was injected before the injection of cisplatin 20 min before and after 4 h. Combined group: Intravenous injection of dexamethasone 10 mg 40 min before injection of cisplatin and ondansetron 8 mg in the first 20 min. After cisplatin was discontinued in both groups, oral ondansetron 4 mg was changed to oral administration twice a day for 2 days. The control rate of nausea and vomiting in the single-use group was 88% and 92%, respectively. 2 to 5d is 76% to 92%. The control rate of nausea and vomiting in the combined group was 92% and 96%, respectively. 2 to 5d is 80% to 96%. There was no statistical difference between the two groups (P>005). The results showed that the effect of ondansetron was definite, and the efficacy of the combined group was reduced by half.