论文部分内容阅读
本文报道二例拉米夫定抗乙型肝炎病毒治疗中出现听力障碍的患者。病例1:患者男性,23岁,间断乏力,食欲不振,腹胀6年,肝功能持续异常,ALT波动在60-170IU/L之间,HBsAg、HBeAg、和抗HBc均阳性,HBVDNA定量波动在10~5拷贝/ml-10~7拷贝/ml之间,6年间曾因黄疸上升反复住院三次,2000年11月予拉米夫定抗病毒治疗,6个月后HBVDNA阴转,ALT正常,HBsAg阴转,HBeAb阳性(出现血清学转换)HB-
This article reports two cases of lamivudine treatment of hepatitis B patients with hearing loss. Case 1: Male patient, 23 years old, intermittent fatigue, loss of appetite, abdominal distension 6 years, abnormal liver function, ALT fluctuations between 60-170IU / L, HBsAg, HBeAg, and anti-HBc were positive, quantitative fluctuations in HBVDNA 10 ~ 5 copies / ml-10 ~ 7 copies / ml, 6 years had repeatedly hospitalized for jaundice three times in November 2000 to lamivudine antiviral therapy, 6 months after HBVDNA negative, ALT normal, HBsAg Negative, HBeAb positive (seroconversion) HB-