本文观察到 Ma 能明显抑制小鼠的自主活动,拮抗苯丙胺和咖啡因的中枢兴奋作用,增强戊巴比妥钠及水合氯醛的中枢抑制作用;扭体法与热刺激法测痛试验显示本品具有镇痛作用,icv 微量的 Ma后,仍能显著提高小鼠的痛阈值,提示其镇痛作用部位可能在中枢;此外,尚观察到本品具有降低大鼠正常体温的作用。实验结果表明,Ma 具有镇静、镇痛、降温等中枢药理作用。 In this paper, it was observed that Ma can significantly inhibit mice’s autonomic activity, antagonize the central stimulant effect of amphetamine and caffeine, and enhance the central inhibition of pentobarbital sodium and chloral hydrate; writhing and thermal stimulation test pain test shows that The product has analgesic effect, and after a trace amount of Ma, icv can still significantly increase the pain threshold of the mouse, suggesting that the site of analgesia may be in the center; in addition, it has been observed that this product has the effect of reducing normal body temperature in rats. The experimental results show that Ma has a central pharmacological effect such as sedation, analgesia, and cooling.