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近一年来,我们在急性高血压性脑出血及蛛网膜下腔出血病人中应用硝苯吡啶以降低血压解除脑血管痉挛,取得了一定效果。资料与方法资料:选87年在我科住院的脑出血病人40例,随机分为服用硝苯吡啶组(服药组)与未服硝苯吡啶组(对照组)。服药组男14例,女6例,平均年龄60岁。对照组男14例,女6例,平均年龄59岁。均符合第二届全国脑血管病学术会议1986年第三次修订的脑血管病诊断要点,并经腰穿或 CT 证实。入院时病人多有神志障碍,以嗜睡、昏睡、昏迷不等。入院后除经甘露醇脱水降颅压及止血药物治疗外,服药组加用硝苯吡啶,药量根据病人血压情况给予10~20mg,一日三次,经口服或鼻饲。对照组则采用复方降压片治疗,给药途径同服药组,入院后即开始用药,15天为一个疗程。
In the past year, we used nifedipine in patients with acute hypertensive intracerebral hemorrhage and subarachnoid hemorrhage to reduce blood pressure and relieve cerebral vasospasm and achieved certain results. Materials and Methods Materials: Forty cases of ICH hospitalized in our department for 87 years were randomly divided into nifedipine group (taking drug group) and nifedipine group (control group). Medication group 14 males and 6 females, average age 60 years old. Control group, 14 males and 6 females, mean age 59 years old. All were in line with the Second National Cerebrovascular Disease Conference in 1986 the third revision of the diagnosis of cerebrovascular disease points, and confirmed by lumbar puncture or CT. Admission patients often have mental disorders, to lethargy, lethargy, coma range. In addition to dehydration by mannitol after descending intracranial pressure and hemostatic drug treatment, the medication group plus nifedipine, the dose according to the patient’s blood pressure given 10 ~ 20mg, three times a day, by oral or nasal feeding. The control group was treated with compound antihypertensive tablets, route of administration with the medication group, began to medication after admission, 15 days for a course of treatment.