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目的:观察复方杏仁面膜对黄褐斑患者血清超氧化物歧化酶(SOD)和丙二醛(MDA)的影响。方法:选择女性黄褐斑患者64例,随机分为治疗组和对照组。治疗组外用复方杏仁面膜,对照组外涂维A酸霜,两组患者均口服维生素C、维生素E,治疗前后分别检测患者血清SOD、MDA水平。结果:治疗组总有效率94.12%,明显高于对照组(P<0.05)。治疗组血清SOD显著升高(P<0.01)、MDA明显降低(P<0.05)。结论:复方杏仁面膜治疗黄褐斑具有抗氧化作用,临床可获得较好效果。
Objective: To observe the effects of compound almond mask on serum superoxide dismutase (SOD) and malondialdehyde (MDA) in patients with melasma. Methods: 64 female patients with chloasma were randomly divided into treatment group and control group. In the treatment group, the compound almond mask was applied externally, and the control group was coated with Vitamin A acid cream. Both groups were given vitamin C and vitamin E orally. The serum SOD and MDA levels were measured before and after treatment. Results: The total effective rate of the treatment group was 94.12%, which was significantly higher than that of the control group (P<0.05). Serum SOD in the treatment group was significantly increased (P<0.01) and MDA was significantly decreased (P<0.05). Conclusion: The compound almond mask has antioxidation effect on chloasma and can obtain better clinical results.