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目的探讨厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压的疗效。方法将柳州市柳城县人民医院2009-06-2010-06收治的60例老年原发性高血压的患者随机分为观察组和对照组,每组30例,对照组单纯采用氢氯噻嗪治疗,观察组在对照组的基础上采用厄贝沙坦治疗,比较两组患者的临床疗效、降压幅度及不良反应。结果观察组显效20例,有效6例,总有效率为86.7%显著高于对照组的66.7%,P<0.05。且观察组治疗后的血压的改善幅度显著高于对照组,P<0.05。两组均未因不良反应而中断治疗。结论厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压病疗效较好,且不良反应小,值得临床推广。
Objective To investigate the efficacy of irbesartan combined with hydrochlorothiazide in the treatment of senile essential hypertension. Methods Sixty elderly essential hypertension patients admitted to Liucheng County People’s Hospital of Liuzhou City from June 2009 to June 2010 were randomly divided into observation group and control group, 30 cases in each group. The control group was treated with hydrochlorothiazide alone. The observation group In the control group based on the use of irbesartan treatment, the clinical efficacy of two groups were compared, blood pressure amplitude and adverse reactions. Results In the observation group, 20 cases were markedly effective and 6 cases were effective. The total effective rate was 86.7%, significantly higher than that of the control group (66.7%, P <0.05). And the observation group after treatment, the improvement of blood pressure was significantly higher than the control group, P <0.05. Neither group discontinued treatment due to adverse reactions. Conclusion Irbesartan combined with hydrochlorothiazide in the treatment of senile essential hypertension is effective, and the adverse reactions are small, worthy of clinical promotion.