为探讨肿瘤坏死因子α（TNF－α）和白细胞介素8（IL－8）在创伤性急性肺损伤（ALI）发生发展中的可能作用，采用兔胸部撞击致创伤性ALI模型，利用酶联免疫法观察伤后说浆及支气管肺泡灌洗液（BALF）中TNF－α及IL－8含量的变化，辅以动脉血氧分压（PaO2），肺湿／干比值和病理 To investigate the possible role of tumor necrosis factor-α (TNF-α) and interleukin-8 (IL-8) in the pathogenesis of traumatic acute lung injury (ALI), traumatic ALI model was induced by thoracic bump in rabbits. Immune method was used to observe the changes of TNF-α and IL-8 levels in plasma and bronchoalveolar lavage fluid (BALF) after injury, supplemented with arterial partial pressure of oxygen (PaO2), lung wet / dry ratio and pathology