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【目的】通过对新生儿血浆蛋白测定结果分析,探讨生后早期血浆蛋白质量对新生儿营养状况评估价值。【方法】选取120例新生儿为研究对象,分以下四组:早产小于胎龄儿组(small for gestational age,SGA)30例,早产适于胎龄儿(appropriate for gestational age,AGA)组30例,足月小于胎龄儿组30例,足月适于胎龄儿组30例。所有研究对象生后24 h内静脉采血测定血浆蛋白进行比较分析。【结果】1)SGA组血浆前白蛋白质量(serum protein mass/pre-albumin,SPM/PA)显著低于AGA组;2)早产儿AGA组白蛋白(albumin,ALB)低于足月儿AGA组;3)早产儿组前白蛋白(prealbumin,PA)及SPM/PA均低于足月儿组。上述差异均有统计学意义(P<0.05)。【结论】1)新生儿早期SPM/PA是评价新生儿营养状况的重要指标;2)SPM/PA还可作为评定胎龄,区分适于胎龄儿和小于胎龄儿的有效指标。
【Objective】 To evaluate the value of early postnatal plasma protein in nutritional status of newborns by analyzing the results of plasma protein determination in newborn. 【Methods】 A total of 120 newborns were enrolled in this study. The subjects were divided into the following four groups: premature labor was less than 30 for small for gestational age (SGA), premature for suitable for gestational age (AGA) group 30 Cases, full-term children less than gestational age group of 30 cases, full-term suitable for gestational age group of 30 cases. All subjects within 24 h after birth venous blood plasma protein for comparative analysis. 【Results】 1) Serum protein mass / pre-albumin (SPM / PA) of SGA group was significantly lower than that of AGA group; 2) Albumin (ALB) Group; 3) prealbumin (prealbumin, PA) and SPM / PA in preterm infants were lower than those in term infants. The differences were statistically significant (P <0.05). 【Conclusion】 1) The early neonatal SPM / PA is an important index to evaluate the nutritional status of neonates; 2) SPM / PA can also be used as a measure of gestational age to distinguish between suitable for gestational age children and gestational age children effective indicators.