为了人血白蛋白、精制破伤风抗毒素、A群脑膜炎球菌多糖菌苗临床应用或人体接种的安全性,使用两种鲎试剂通过鲎试验检测热原质.结果表明,一种新型的特异性鲎试剂优于普通鲎试剂,其表现为减少或消除了假阳性反应,与家兔热原质试验阴性结果相符.因此,使用新型鲎试剂有望扩大我国药品以细菌内毒素检查法代替家兔热原质检测试验的品种,使中国药典的这一检测标准,能在保障临床用药安全的前提下,早日达到发达国家水平. For human serum albumin, purified tetanus antitoxin, clinical application of Group A meningococcal polysaccharide vaccine or human inoculation safety, pyrogen test was performed using the two kinds of test reagents, and the results showed that a new type of specificity鲎 reagent is superior to ordinary 鲎 reagent, which showed to reduce or eliminate the false positive reaction, which is consistent with the negative result of the rabbit pyrogen test .Therefore, the use of new 鲎 reagent is expected to expand our drugs to bacterial endotoxin test instead of rabbit fever The variety of the test of the quality test makes this test standard of Chinese Pharmacopoeia achieve the level of developed countries as soon as possible under the premise of ensuring the safety of clinical medication.