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There is long-standing debate about sensate versus non-sensate free microvascular flaps among microsurgeons.The principle of connecting not only the vascular supply,but also sensitive nerves,in free tissue transfer is attractive.However,increased operating time and partial spontaneous innervation led to the common decision to restrict microsurgical tissue transfer to the vascular anastomosis and to leave the nerves untreated.Nevertheless,in special cases such as breast reconstruction or extremity reconstruction,the question about sensory nerve coaptation of the flaps remains open.We present our experience with free microvascular tissue transfer for breast and extremity reconstruction and compare the data with previous literature and conclude that most free flap surgeries do not benefit from nerve coaptation.