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对空腹血糖>11.1mmol/L的86例初诊2型糖尿病患者随机分为CSⅡ组、每日MDI组,分析比较两组患者血糖达标时间、胰岛素用量、低血糖发生率及停用胰岛素后对患者长期血糖良好控制的影响。结果CSⅡ组显示出快速稳定的降血糖效果,44例患者的餐前、餐后、睡前及夜3时的血糖分别于治疗后(2.9±1.6)d、(2.7±1.8)d、(3.1±1.5)d、(2.5±1.1)d达到良好控制,与每日MDI组比较,血糖达标时间明显缩短,且全天胰岛素用量、低血糖发生率明显低于每日MDI组,且在停用胰岛素治疗1年后单纯饮食及运动治疗血糖仍能得到良好控制的例数明显高于每日MDI组。结论对伴有明显高血糖的初诊2型糖尿病患者,短期CSⅡ强化治疗具有快速稳定控制血糖和停用胰岛素后对患者长期血糖良好控制的作用。
Eighty-six patients with newly diagnosed type 2 diabetes with fasting blood glucose> 11.1mmol / L were randomly divided into CSII group and daily MDI group. The patients’ blood glucose compliance time, insulin dosage, incidence of hypoglycemia and insulin withdrawal were compared between the two groups Effects of long-term good glycemic control. Results The fasting and stable hypoglycemic effect was observed in CSⅡ group. The blood glucose levels of pre-meal, post-meal, pre-night and post-night blood glucose in 44 patients were 2.9 ± 1.6 days, 2.7 ± 1.8 days, ± 1.5) d and (2.5 ± 1.1) days respectively. Compared with the daily MDI group, the time of reaching the standard of glycemic control significantly shortened, and the daily insulin dosage and the incidence of hypoglycemia were significantly lower than those of the daily MDI group One year after insulin therapy, simple diet and exercise therapy, blood glucose can still be well controlled cases were significantly higher than the daily MDI group. Conclusions Short-term CSI intensive treatment of patients with newly diagnosed type 2 diabetes mellitus with significant hyperglycemia has the effect of long-term good glycemic control in patients with rapid and stable control of blood glucose and insulin withdrawal.