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一、类型和命名 非何杰金氏恶性淋巴瘤(non-Hodgkin’s malignant lymphoma)是由淋巴网状组织(lymphoreticular tissue)发生的原发性肿瘤,主要发生于淋巴结,也可发生于结外。淋巴网状组织是由原始性网状细胞、淋巴细胞、组织细胞等构成的组织。一般认为淋巴细胞和组织细胞是由原始性网状细胞分化成熟而形成的。非何杰金氏恶性淋巴瘤就是由这些细胞的肿瘤性增生所形成的肿瘤。由于这些瘤性细胞的分化程度不同,其组织结构和恶性程度也有所不同。 Rappaport(简写为R.氏)着眼于瘤细胞的分化程度,把这一类淋巴瘤分为五个类型(详
I. Types and Nomenclature Non-Hodgkin’s malignant lymphoma is a primary tumor of the lymphoreticular tissue that occurs primarily in the lymph nodes and can also occur outside the nodules. Lymphoid reticular tissue is composed of primitive reticular cells, lymphocytes, tissue cells and other organizations. It is generally believed that lymphocytes and tissue cells are formed by the differentiation and maturation of primitive reticulocytes. Non-Hodgkin’s malignant lymphoma is a tumor formed by the tumor’s proliferation of these cells. Due to the different degree of differentiation of these tumor cells, their histological structure and degree of malignancy are also different. Rappaport (abbreviated R.’s) focuses on the degree of tumor cell differentiation, this type of lymphoma is divided into five types