本文探讨鲍温(Bowen)样丘疹病的临床病理特征、鉴别诊断及原因。对8例Bowen样丘疹病进行临床病理分析,用免疫组化S-P法检测HPV16/18抗原及P53蛋白。结果表明,Bowen样丘疹病的诊断应该结合临床特征及镜下表现,排除Bowen样病,该病属于良性病变,但需要密切临床随访。 This article discusses the clinicopathological features, differential diagnosis and causes of Bowen papulosis. Eight cases of Bowenoid papulosis were analyzed clinically and pathologically. HPV16 / 18 antigen and P53 protein were detected by immunohistochemical S-P method. The results show that Bowen-like papulosis diagnosis should be combined with clinical features and microscopic appearance, exclude Bowen-like disease, the disease is benign, but requires close clinical follow-up.