目的　检测天然除虫菊酯的免疫毒性。方法　设对照组和 3个剂量组。SD大鼠经口染毒 3个月。分别检测白细胞总数、分类及免疫器官脏 /体比和组织病理学检查。结果　与对照组相比 ,各剂量组白细胞总数、分类及免疫器官脏 /体比 ,其差异均无统计学意义 (P >0 0 5 )。免疫器官组织病理学检查 ,未观察到明显组织病理学改变。结论　天然除虫菊酯经口染毒 3个月 ,未观察到明显的免疫毒性效应。 Objective To detect the immunotoxicity of natural pyrethrins. Methods The control group and three dose groups. SD rats were orally infected for 3 months. The total number of leukocytes, the classification of organs and the organs / organs of immune organs and histopathological examination were respectively examined. Results Compared with the control group, there were no significant differences in the total number of leukocytes, the classification of organs and the ratio of organs to body weight of the immune organs in each dose group (P> 0.05). Immunohistochemical histopathological examination, no significant histopathological changes were observed. Conclusion Natural pyrethrins were orally administered for 3 months and no significant immunotoxic effects were observed.