论文部分内容阅读
目的:观察冠心止痛合剂治疗冠心病心绞痛的临床疗效。方法:将70例冠心病心绞痛患者随机分为治疗组与对照组两组,每组各35例。所有患者均接受一般治疗,对照组予舒血宁注射液及硝酸甘油注射液静点,1次/d,同时口服硝酸异山梨酯片,每次10 mg,3次/d,治疗组在上述治疗基础上口服中药冠心止痛合剂,并随证加减,疗程为4周,疗程结束后观察疗效。结果:两组治疗后临床疗效比较,治疗组为91.4%,对照组为74.3%,两组相比,有统计学差异(P<0.05)。在心电图疗效比较中,治疗组有效率为85.7%,对照组有效率为68.6%,两组相比,有统计学差异(P<0.05)。治疗后治疗组发作次数、持续时间及平均住院时间均少于对照组,两组相比,有统计学差异(P<0.05)。两组治疗后CK-MB及c Tn I水平比较中,治疗组明显低于对照组,两组相比,差异有统计学意义(P<0.05)。结论:口服冠心止痛合剂可以明显提高临床疗效及心电图疗效,同时改善心绞痛症状,缩短住院时间,还能有效地降低CK-MB及心肌钙蛋白水平,且无明显不良反应,值得临床推广使用。
Objective: To observe the clinical effect of Guanxin Zhitong Mixture in treating angina pectoris of coronary heart disease. Methods: Seventy patients with coronary heart disease and angina pectoris were randomly divided into treatment group and control group, with 35 cases in each group. All patients received general treatment, the control group Shuxuening injection and intravenous injection of nitroglycerin, 1 / d, while oral isosorbide dinitrate tablets, each 10 mg, 3 times / d, the treatment group in the above On the basis of oral Chinese medicine treatment of coronary heartache mixture, and with the addition and subtraction card, treatment for 4 weeks after the end of treatment to observe the effect. Results: The clinical efficacy of the two groups after treatment was 91.4% in the treatment group and 74.3% in the control group. There was a significant difference between the two groups (P <0.05). In the ECG comparison, the effective rate was 85.7% in the treatment group and 68.6% in the control group. There was a significant difference between the two groups (P <0.05). After treatment, the number of episodes, duration and average length of hospital stay in the treatment group were less than those in the control group. There was significant difference between the two groups (P <0.05). After treatment, the levels of CK-MB and cTn I in the treatment group were significantly lower than those in the control group, the difference was statistically significant (P <0.05). Conclusion: Guanxin Zhitong Mixture can significantly improve clinical curative effect and electrocardiogram curative effect, meanwhile improve angina pectoris symptom, shorten hospitalization time, reduce CK-MB and cardiac troponin, and have no obvious adverse reactions. It is worthy of clinical application.