By means of oral administration or extal application, hormone can be widely used in clinical treatment of various diseases. However, along with the therapeutic effects, hormonotherapy can also bring about certain side effects to the human body.In the two years of clinical practice in Germany from 2002-2004, the author of this article had applied acupuncture in replacement of hormonotherapy to treat many diseases, and obtained certain therapeutic effects. The following is an introduction of the clinical experience in this aspect.