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目的:多中心调查分析多重耐药菌(MDRO)医院感染肺炎的危险因素。方法:选取本地区3所医院2013年3月-2015年3月收治的因5种MDRO及对应敏感菌导致的医院感染肺炎患者作为实验对象,其中出现5种MDRO医院感染肺炎患者为实验组(436例),出现对应5种敏感菌医院感染肺炎患者为对照组(425例),调查分析MDRO医院感染肺炎的危险因素,对比两组患者预后情况。结果:实验组出现耐药菌与敏感菌混合感染的有213例(48.85%),对照组201例(47.29%);发生MDRO医院感染肺炎的独立危险因素主要是入住重症监护室(ICU)、机械通气史、使用抗菌药物等等。结论:增加患者出现MDRO医院感染肺炎风险因素主要是入住ICU、实施各种侵入性操作及采用抗菌药物等等。
PURPOSE: A multicenter study was conducted to analyze the risk factors for hospital-acquired pneumonia in multi-drug resistant bacteria (MDRO). Methods: From March 2013 to March 2015 in our hospital, 5 hospital patients with pneumonia due to MDR and corresponding susceptible strains were selected as experimental subjects. Five patients with MDRO hospital-acquired pneumonia were selected as the experimental group ( 436 cases). There were 425 patients with nosocomial pneumonia corresponding to 5 kinds of sensitive bacteria. The risk factors of pneumonia in MDRO hospital were investigated and compared, and the prognosis of two groups was compared. Results: There were 213 cases (48.85%) in the experiment group and 201 cases (47.29%) in the control group. The independent risk factors of pneumonia in MDRO hospital were mainly admitted to intensive care unit (ICU) History of mechanical ventilation, use of anti-bacterial drugs and more. CONCLUSIONS: Increasing the risk factors for pneumonia in MDRO hospital patients is mainly in ICU, invasive procedures and the use of antimicrobial agents.