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甲亢是一种常见内分泌疾病。内科抗甲亢药物治疗疗程长,复发率高,约60％。外科治疗属创伤性,一些并发症较严重,其复发率13.6％。~(131)Ⅰ治疗简单,疗效高,复发率低,约1～4％,虽有少数病人可出现甲状腺功能低下(简称甲低),但只要掌握好病情及剂量是可以减少甲低发生率的,而且服用甲状腺片甲低可完全纠正。 资 料 与 方 法 一、我院经~(131)Ⅰ治疗后2～5年能随访到的患者共118人,其中男35人,女83人。平均年龄43岁(26～68岁)。多数是经内科治疗后复发患者,少数为手术治疗后复发患者。经甲状腺吸~(131)Ⅰ功能试验、甲状腺扫描及触诊法结合估计甲状腺重量,以计算服~(131)Ⅰ剂量。本组甲状腺平均重量61.4克,投~(131)Ⅰ剂量平均2.41 MBq/g(65μCi/g),平均总剂量196MBq(5.3mCs)。以1次口服为原则,其中2次服药25人,3次服药3人。
Hyperthyroidism is a common endocrine disease. Medical anti-hyperthyroidism drug treatment of long course, the recurrence rate is high, about 60%. Surgical treatment is traumatic, some more serious complications, the recurrence rate was 13.6%. ~ (131) Ⅰ treatment is simple, high efficacy, low recurrence rate of about 1-4%, although there may be a small number of patients with hypothyroidism (hypothyroidism), but as long as the condition and dose can reduce the incidence of hypothyroidism , And taking thyroid tablets A low can be completely corrected. Materials and Methods A total of 118 patients, including 35 males and 83 females, were followed up from 2 to 5 years after treatment with ~ (131) Ⅰ in our hospital. The average age is 43 years old (26 to 68 years old). Most are relapsed after medical treatment of patients, a small number of recurrence patients after surgery. Thyroid suction ~ (131) Ⅰ function test, thyroid scan and palpation combined with the estimated thyroid weight to calculate the dose of ~ (131) Ⅰ. The average thyroid weight of 61.4 g, ~ (131) I dose average 2.41 MBq / g (65μCi / g), the average total dose of 196MBq (5.3mCs). Take the principle of 1 oral administration, of which 25 were taken twice and 3 took 3 times.