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目的:分析原发性胃肠道粘膜相关淋巴组织淋巴瘤病理特点。方法:回顾性50例原发性胃肠道黏膜相关淋巴组织淋巴瘤患者的病例资料,总结该类患者的病例特征。结果:患者均表现为淋巴瘤细胞浸润黏膜表层被覆上皮或腺体,均可见腺体上皮破坏。无CBL细胞低度恶性35例,低密度性合并小区域高密度恶性淋巴瘤成分9例,高度恶性MALT淋巴瘤6例,黏膜下层浸润4例,浆膜内浸润41例,浸润型突破浆膜外4例。结论:GIL-MALT多发于中老年男性患者,发病部位以胃部多见。患者临床表现无特异性,误诊率高。疾病发生与HP感染有一定关系,病灶的大小与组织学分类有关,大病灶的恶性程度更高。
Objective: To analyze the pathological characteristics of primary gastrointestinal mucosa-associated lymphoid tissue lymphoma. Methods: The clinical data of 50 patients with primary gastrointestinal mucosa-associated lymphoid tissue lymphoma were retrospectively reviewed. The case characteristics of these patients were summarized. Results: The patients showed lymphoid cell infiltration mucosal epithelial or glandular epithelium, both visible epithelial damage. No CBL low malignant tumor in 35 cases, low-density small regional high-density malignant lymphoma in 9 cases, 6 cases of high-grade MALT lymphoma, submucosal infiltration in 4 cases, serosal invasion in 41 cases, infiltration of breakthrough serosa 4 cases outside. Conclusion: GIL-MALT is frequently found in middle-aged and elderly male patients. Patients with non-specific clinical manifestations, misdiagnosis rate. The occurrence of the disease and HP infection have a certain relationship, the size of the lesion and histological classification, the greater the degree of malignancy.