英国每年大约有50例钩端螺旋体病(以下简称钩体病)发生,其中10％发生急性肾功能衰竭,病死率约为5％,多死于伴发黄疸的肾功能衰竭。6例均系男性,年龄23～49岁,起病后2～10天内大多因发热、头痛、背痛、腹痛、呕吐、腹泻、肌痛、关节痛、躯干皮肤散在出血点、随后发生黄疸和少尿而入院。患者血尿素氮240～600mg％;血小板值低;常规凝血试验结果大多正常。6例中2例钩端螺旋体(以下简称钩体)补体结合试验结果阳性(效 About 50 cases of leptospirosis (hereinafter referred to as leptospirosis) occur each year in the UK, of which 10% develop acute renal failure with a mortality rate of about 5% and more often die of renal failure with jaundice. 6 cases were male, aged 23 to 49 years old, 2 to 10 days after onset mostly due to fever, headache, back pain, abdominal pain, vomiting, diarrhea, myalgia, joint pain, torso scattered bleeding in the skin, followed by jaundice and Oliguria and admission. Patients with blood urea nitrogen 240 ~ 600mg%; platelet value is low; conventional coagulation test results are mostly normal. 6 cases in 2 cases of Leptospira (hereinafter referred to as leptospirosis) complement fixation test results were positive