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目的:研究血脂与血尿酸浓度变化在老年脂肪肝患者诊断中的价值。方法:选取我院三年来健康体检时确诊为脂肪肝患者的80例为观察组,体检结果为健康正常人的80例为对照组。测定两组总胆固醇、甘油三酯、血尿酸、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇的值,将检测结果进行对比。结果:两组检测结果对比,观察组的总胆固醇高于对照组的(x2=11.358,P=0.015);观察组的甘油三酯值高于对照组(x2=7.456,P=0.035);观察组中的血尿酸,高于对照组值(x2=9.875,P=0.029)、低密度脂蛋白胆固醇的值,高于对照组(x2=12.037,P=0.013),高密度脂蛋白胆固醇低于对照组(x2=5.149,P=0.041)。在轻、中、重度三组脂肪肝患者中,中度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于轻度脂肪肝患者,高密度脂蛋白含量低于轻度脂肪肝患者,P<0.05,差异有统计学意义;重度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于中度脂肪肝患者,高密度脂蛋白含量低于中度脂肪肝患者,P<0.05,差异有统计学意义。结论:脂肪肝病变程度越大,脂肪肝患者总胆固醇、甘油三酯、血尿酸、低密度脂蛋白胆固醇的值越高,高密度脂蛋白胆固醇的值越低,血脂与血尿酸浓度变化可作为诊断脂肪肝疾病的依据,可实现早发现、早治疗,值得应用。
Objective: To study the value of blood lipid and serum uric acid concentration in the diagnosis of fatty liver in elderly patients. Methods: Eighty patients with fatty liver diagnosed during the three years of physical examination in our hospital were selected as the observation group, and 80 healthy people were selected as the control group. The total cholesterol, triglycerides, serum uric acid, high density lipoprotein cholesterol and low density lipoprotein cholesterol in the two groups were measured and the results were compared. Results: The total cholesterol in the observation group was higher than that in the control group (x2 = 11.358, P = 0.015). The triglyceride value in the observation group was higher than that in the control group (x2 = 7.456, P = 0.035) The values of serum uric acid in the group which were higher than the control group (x2 = 9.875, P = 0.029) and LDL cholesterol were higher than those in the control group (x2 = 12.037, P = 0.013) Control group (x2 = 5.149, P = 0.041). Among mild, moderate and severe fatty liver patients, the patients with moderate fatty liver had higher levels of total cholesterol, triglyceride, blood uric acid and low density lipoprotein than those with mild fatty liver, the content of high density lipoprotein was lower than that of light Degree of fatty liver disease, P <0.05, the difference was statistically significant; the patients with severe fatty liver had higher total cholesterol, triglyceride, serum uric acid and low density lipoprotein than those with moderate fatty liver, the content of high density lipoprotein was lower than Moderate fatty liver patients, P <0.05, the difference was statistically significant. Conclusion: The greater the degree of fatty liver disease, the higher the total cholesterol, triglyceride, serum uric acid, low density lipoprotein cholesterol in patients with fatty liver, the lower the value of high density lipoprotein cholesterol, the change of blood lipid and serum uric acid concentration can be used as Diagnosis of fatty liver disease based on early detection and early treatment, it is worth to apply.