药物性耳中毒意味着在细胞水平上的内耳末梢受体发生机能性(可逆性)或器质性(非可逆性)的变化。耳中毒症于1945年链霉素氨基甙类抗菌素问世以后才日益受到重视,在此以前已知有许多约物可致耳中毒(奎宁、水杨酸、尼古丁、乙醇、土荊芥油和汞、砷、铅等)。近年来,速尿和利尿酸等利尿剂的应用,也有引起一过性耳聋和永久性耳聋的报道。叮致耳中 Medicated ototoxicity means that there is a functional (reversible) or an organic (irreversible) change in the inner ear terminal receptors at the cellular level. Ear aurisosis is gaining increasing attention after the advent of streptomycin aminoglycoside antibiotics in 1945, where many substances known to cause ototoxicity (quinine, salicylic acid, nicotine, ethanol, locust oil, and mercury , Arsenic, lead, etc.). In recent years, furosemide and diuretic diuretics, such as the application, but also caused a transient deafness and permanent deafness reports. Bite in the ears