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目的探讨比索洛尔联合辛伐他汀治疗老年不稳定型心绞痛(UA)患者的临床疗效。方法选取2013年8月至2014年10月朝阳市中心医院收治的52例老年UA患者作为研究对象,按随机数字表法将其分为对照组和观察组,各26例。对照组患者睡前口服辛伐他汀,观察组患者在对照组基础上给予比索洛尔,比较两组患者的临床疗效及不良反应发生情况。结果观察组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论比索洛尔联合辛伐他汀治疗老年UA临床疗效明显,可明显改善患者的临床症状,且不良反应少,临床用药安全高。
Objective To investigate the clinical efficacy of bisoprolol combined with simvastatin in the treatment of elderly patients with unstable angina pectoris (UA). Methods Twenty-two elderly UA patients admitted to Chaoyang Central Hospital from August 2013 to October 2014 were selected as study subjects and divided into control group and observation group according to random number table method, with 26 cases in each group. The patients in the control group were given simvastatin orally before going to bed and the patients in the observation group were given bisoprolol on the basis of the control group. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that of the control group (P <0.05). Conclusion Bisoprolol combined with simvastatin has obvious curative effect on elderly UA, which can significantly improve the clinical symptoms of patients with less adverse reactions and high safety of clinical medication.