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通过对２型糖尿病（ＮＩＤＤＭ）核心家系的分析，探讨了遗传因素在核心家系成员中所起作用的程度。结果表明：病例核心家系一级亲属ＮＩＤＤＭ 的发病率非常显著的高于对照组，χ２ ＝ １７．０，Ｐ＜ ０．００１，相对危险度（ＲＲ）为３．３０，９５％ 可信区间为１．８０～６．０５。不论父母、同胞和子女，均以病例亲属的发病率显著高于对照；病例组各亲属中，不论男女和年龄，标准化发病率比（ＳＩＲ）均明显高于对照人群的１００，经统计学Ｚ检验有极显著意义；病例核心家系的ＲＲ、归因危险度（ＡＲ）％ 也明显较高，进一步说明血缘关系与ＮＩＤＤＭ 之间有较强的联系。
Through the analysis of type 2 diabetes (NIDDM) core pedigrees, the extent to which genetic factors play a role in core family members is explored. The results showed that the incidence of NIDDM was significantly higher in the first degree relatives of the core family members than in the control group (χ2 = 17.0, P <0.001), and the relative risk (RR) was 3.30 and the 95% confidence interval 1.80 ~ 6.05. Both parents, siblings and children, were relatives of the incidence was significantly higher than the control; case of relatives, regardless of age and sex, the standardized incidence rate (SIR) were significantly higher than the control population of 100, the statistical Z The test had a very significant significance. The RR and attributional risk (AR)% of case-core pedigrees were also significantly higher, further illustrating the strong association between blood relationship and NIDDM.