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测定了示踪浓度下Ｇａ（Ⅲ）在ＨＣｌ－乙酸丁酯体系中的分配比Ｄ。实验表明，ＨＣｌ浓度为６ｍｏｌ／ｌ时，Ｄ值最高，达５×１０￣２。当相比为１，ＨＣｌ浓度为５．５－８．０ｍｏｌ／ｌ时，萃取率Ｅ≥９８％。在相同条件下，共存的ＺｎＣｌ＿２浓度＜２ｍｏｌ／ｌ时，Ｅ不低于９６％。采用乙酸丁酯萃取法从质子束照射后的Ｚｎ靶中制备枸橼酸镓［￣（６７）Ｇａ］注射液。萃取酸度为６ｍｏｌ／ｌＨＣｌ，Ｚｎ离子浓度≤２ｍｏｌ／ｌ，萃取前用ＴｉＣｌ＿３还原痕量Ｆｅ（Ⅲ）为Ｆｅ（Ⅱ），Ｇａ（Ⅲ）用水反萃。产品的核纯度～１００％，放化纯度＞９０％，Ｚｎ、Ｔｉ、Ｆｅ、Ｃｕ、Ｃｄ、Ｐｂ的浓度低于或接近１ｍｇ／ｌ，异常毒性检查合格，各项指标均符合中国药典和美国药典要求。化学产率为（９２±２）％，制备时间＜３ｈ。
The distribution ratio Ga of Ga (Ⅲ) in HCl-butyl acetate system at the tracer concentration was determined. Experiments show that, HCl concentration of 6mol / l, the highest value of D, up to 5 × 10 ~ 2. When compared to 1, HCl concentration of 5.5-8.0 mol / l, the extraction rate E ≥ 98%. Under the same conditions, the coexistence of ZnCl2 concentration <2mol / l, E not less than 96%. Gallium citrate [~ (67) Ga] injection was prepared by butyl acetate extraction from Zn target after proton beam irradiation. Extraction of acidity of 6mol / lHCl, Zn ion concentration ≤ 2mol / l, before extraction TiCl_3 reduction trace Fe (Ⅲ) Fe (Ⅱ), Ga (Ⅲ) water back-extraction. The purity of the product is about 100% and the radiochemical purity is more than 90%. The concentrations of Zn, Ti, Fe, Cu, Cd and Pb are lower or close to 1mg / l, and the abnormal toxicity check is satisfactory. All the indexes are in line with the Chinese Pharmacopoeia and the United States Pharmacopoeia requirements. Chemical yield was (92 ± 2)%, preparation time <3h.