随着恶性肿瘤诊疗水平不断提高,患者远期生存率普遍延长,发生另一原发癌的机会也随之增加。有资料显示,肿瘤患者中第二原发癌（secon primarycancer,SPC）的发生率高达12％[1],在头颈肿瘤患者中,SPC的发生率为7％,第三原发癌的发生率为0.6％,且第二原发癌的多发部位仍在头颈部[2]。在某些病例中,SPC甚至成为主要致死原因,因此多原 With the continuous improvement of the diagnosis and treatment of malignant tumors, the long-term survival rate of patients generally extended, the chance of another primary cancer also increases. Data show that the incidence of second primary cancer in patients with cancer (secon primarycancer, SPC) up to 12% [1], in patients with head and neck cancer, the incidence of SPC was 7%, the incidence of the third primary cancer Is 0.6%, and the second primary cancer is still head and neck in multiple parts [2]. In some cases, SPC is even the leading cause of death and is therefore polybasic