论文部分内容阅读
目的::观察眼轮匝肌平行直刺联合眼周穴位针刺法治疗偏侧面肌痉挛患者的疗效,为治疗面肌痉挛提供理论依据。方法::系列病例研究。收集2018年12月至2020年12月在温州医科大学附属眼视光医院中医眼科门诊诊断为偏侧面肌痉挛的患者60例,按照随机数字表法分为治疗组和对照组,每组30例。治疗组接受眼轮匝肌平行直刺联合眼周穴位针刺法;对照组口服盐酸硫必利片、银杏叶胶囊、甲钴胺胶囊。2组患者治疗2周后根据Cohen评分表评价面肌痉挛严重程度及频率。患者痉挛严重程度及频率分级在治疗前后的比较采用n t检验或秩和检验。n 结果::治疗2周后,治疗组与对照组患者面肌痉挛分级程度均有一定的下降。与治疗前相比,治疗组患者痉挛强度及频率分级的比较差异有统计学意义(n Z=-2.67,n P=0.008;n Z=-2.45,n P=0.014);对照组虽然面肌痉挛强度有一定的下降,但治疗前后差异无统计学意义。治疗组较对照组痉挛强度及频率分级改善明显,差异有统计学意义(n t=-2.04,n P=0.042;n t=-1.99,n P=0.047);治疗组总有效率为87%;对照组总有效率为53%,2组差异有统计学意义(n χ2=11.81,n P=0.008)。随访3个月后,治疗组中有1例复发,复发率为3%;对照组中有6例复发,复发率20%,2组差异有统计学意义(n χ2=4.04,n P=0.044)。n 结论::眼轮匝肌平行直刺联合眼周穴位针刺法在治疗面肌痉挛方面有良好且确定的疗效,并且可以最大限度改善面肌痉挛症状,疗效优于传统治疗方法,适合临床应用。“,”Objective::To observe and study the efficacy of parallel direct puncture of orbicularis oculi muscle combined with periocular acupuncture in the treatment of patients with partial side hemifacial spasm, and to provide a theoretical basis for this treatment.Methods::This was a serial case study. Sixty patients diagnosed with partial side hemifacial spasm in the Eye Hospital, Wenzhou Medical University from December 2018 to December 2020 were randomly divided into a treatment group and control group according to the random number table method, with 30 patients in each group. The treatment group were treated with parallel direct puncture of the orbicularis oculi muscle combined with periocular acupuncture, while the control group was treated with tiapril hydrochloride tablets, ginkgo biloba capsules and mecobalamide capsules. After 2 weeks of treatment, the severity and frequency of the partial side hemifacial spasm were evaluated according to the Cohen scale. The comparison of the patients’ spasticity severity and frequency before and after treatment conformed to a normal distribution using the n t-test or the rank sum test.n Results::After 2 weeks of treatment, there was a certain decrease in the graded degree of the hemifacial spasm in both the treatment and control groups. Compared with the pre-treatment period, the improvement in the graded degree of spasm intensity and frequency in the treatment group was statistically significant (n Z=-2.67, n P=0.008; n Z=-2.45, n P=0.014). Although there was some decrease in the degree of hemifacial spasticity intensity in the control group, there was no statistically significant difference in improvement over the pre-treatment period. Compared to the control group, the improvement in spasticity intensity and frequency classification was significant in the treatment group (n t=-2.04, n P=0.042;n t=-1.99, n P=0.047). The total effective rate was 87% in the treatment group and 53% in the control group, with a statistically significant difference between the two groups (n χ2=11.81, n P=0.008). The results of the 3-month follow-up showed that there was 1 recurrence in 30 patients in the treatment group, with a recurrence rate of 3%, and 6 recurrences in 30 patients in the control group, with a recurrence rate of 20%, with a statistically significant difference between the two groups (n χ2=4.04, n P=0.044).n Conclusion::Parallel direct puncture of the orbicularis oculi muscle combined with periocular acupuncture has good and definite efficacy in the treatment of hemifacial spasm, and can improve the symptoms of hemifacial spasm to the maximum extent. The efficacy is better than for the traditional treatment and is suitable for clinical application.