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[目的]评价射波刀立体定向放射治疗技术治疗早期原发性肝癌的短期疗效和不良反应。[方法]对50例无法进行手术切除或拒绝手术治疗的早期原发性肝癌行射波刀立体定向放射治疗。肿瘤直径0.6~5.0cm,单次分割剂量4~12Gy,照射次数为3~8次,肿瘤剂量(PTV)36~57Gy,连续照射。[结果 ]随访13~51个月,完全缓解(CR)41例(82.0%),部分缓解(PR)8例(16.0%),稳定(SD)0例,进展(PD)1例(2.0%),有效率(CR+PR)为98.0%,1、2、3年总生存率为100.0%、90.0%、76.0%。[结论]射波刀是治疗早期肝癌较有效的手段,且不良反应较小。
[Objective] To evaluate the short-term curative effect and adverse reaction of radiotherapy knife stereotactic radiotherapy in the treatment of early-stage primary liver cancer. [Method] Fifty cases of early primary hepatocellular carcinoma who could not be surgically removed or refused surgical treatment were treated with radiosophageal stereotactic radiotherapy. Tumor diameter 0.6 ~ 5.0cm, a single dose of 4 ~ 12Gy, irradiation times of 3 to 8 times, tumor dose (PTV) 36 ~ 57Gy, continuous irradiation. [Results] 41 cases (82.0%) were completely relieved (CR), 8 cases (16.0%) were partially relieved (PR), 0 cases were stable (SD) and 1 case was progressive (PD) ), And the effective rate (CR + PR) was 98.0%. The overall survival rates at 1, 2 and 3 years were 100.0%, 90.0% and 76.0%. [Conclusion] The radiosurgery is a more effective method for the treatment of early liver cancer with less adverse reactions.