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本文报告6例有严重瘙痒的真性红细胞增多症,男2,女4,年龄58～76岁.均有不同程度的肝脾肿大.平均Hb为18.2g(范围17.1～19.5),白细胞数19,000(12,500～26,000),血小板数48.5万(18万～90万),红细胞容量为40～60ml/kg(正常26～35);骨髓检查显示缺铁粒性增生.尽管采取了充分的血液学控制措施,但瘙痒仍继续.单服赛庚啶或合并服用赛庚啶和甲腈咪胺均无效.此时检查发现瘙痒为缺铁所致,血清铁含量为3～10μmol/l(正常7～27),铁传递蛋白为3.5～
In this paper, 6 cases of polycythemia vera with severe pruritus were reported, male and female 2, female 4, aged 58 to 76. All had varying degrees of hepatosplenomegaly with an average Hb of 18.2g (range 17.1-19.5) and a white blood cell count of 19,000 (12,500-26,000), platelet count 485,000 (180,000-900,000), erythrocyte volume 40-60 ml / kg (normal 26-35), and bone marrow examination showed micronized iron-deficiency hyperplasia despite adequate hematological control Measures, but the itching is still continued single-dose cyproheptadine or combined cyproheptadine and cimetidine invalid .At this time found itching due to iron deficiency, serum iron content of 3 ~ 10μmol / l (normal 7 ~ 27), iron transfer protein is 3.5 ~