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目的:探讨联合干预预防孕妇妊娠期高血压疾病的效果,为妊娠期高血压疾病的预防提供理论依据。方法:选取2012年1月~2013年1月在该院建卡孕检的孕妇509名,随机分为3组。A组202名孕妇孕期进行补铁、钙、叶酸、维生素B12等药物干预,B组200名孕妇进行运动调节、体重管理等针对性干预,C组107名孕妇进行常规孕产期教程和产检,比较3组的妊娠期高血压疾病的发病率。结果:A组孕妇的血钙、铁、叶酸、维生素B12水平均高于C组(P<0.05),A组孕妇的血钙、铁水平均高于B组(P<0.05),B组孕妇的血钙、铁水平均高于C组(P<0.05),A组孕妇妊娠期高血压疾病、胎儿生长受限(FGR)的发生率均明显低于C组(P<0.05)。结论:预防性地进行补钙、铁、叶酸、维生素B12及运动调节、体重管理等联合干预,可以降低妊娠期高血压疾病的发生率。
Objective: To explore the effect of combined intervention in preventing pregnancy-induced hypertension in pregnant women and to provide a theoretical basis for the prevention of hypertensive disorders in pregnancy. Methods: From January 2012 to January 2013, 509 pregnant women who underwent pregnancy test in the hospital were randomly divided into three groups. A group of 202 pregnant women during pregnancy iron, calcium, folic acid, vitamin B12 and other drug interventions, B group of 200 pregnant women exercise regulation, weight management and other targeted interventions, C group of 107 pregnant women routine pregnancy course and childbirth, The incidence of gestational hypertension was compared between the three groups. Results: The levels of serum calcium, iron, folic acid and vitamin B12 in group A were significantly higher than those in group C (P <0.05). The levels of serum calcium and iron in group A were higher than those in group B (P <0.05) (P <0.05). The incidence of gestational hypertension and FGR in group A were significantly lower than that in group C (P <0.05). Conclusion: Preventive combination of calcium, iron, folic acid, vitamin B12 and motor regulation, weight management and other interventions can reduce the incidence of hypertensive disorders during pregnancy.