目的:调查极低出生体重(ELBW)存活婴儿(出生体重:401-1000 g)生后18-22个月时评估神经发育及身体发育中可能存在的差异。方法:将来自1483例ELBW婴儿幸存者的数据作回顾性研究。其出生于1993年2月至1994年12月,均就诊于国家儿童健康和人类发展机构的新生儿研究网络组织中心。对尊从18-22个月追踪随访的孩子、随访但没有做评定的孩子或者没有随访的孩子进行了4个方面结局的比较:①婴儿发育的Bayley评分,第2版,智力发育指数(MDI) <70;②精神运动发育指数(PDI)<70;③缺乏或存在脑瘫;④按照年龄推算其出生体重低于第10个百分点。使用Logistic回归模型来预测这些没有跟踪评价儿童可能的结果,再将预测的分布概率用于组间的比较。结果:与失去随访的儿童相比,那些一直随访的儿童更有可能是多胎产之一,已经接受生后糖皮质激素且曾经 PURPOSE: To assess possible differences in neurodevelopment and body development at 18-22 months after birth in very low birth weight (ELBW) surviving infants (birth weight: 401-1000 g). METHODS: Data from 1483 ELBW infant survivors were retrospectively studied. Born in February 1993 to December 1994, all of them were treated at the Neonatal Research Network Organization Center of the National Child Health and Human Development Agency. Four follow-up comparisons were made among children who followed follow-up from 18 to 22 months, follow-up but no assessment or no follow-up: ① Infant’s Bayley score, 2nd edition, Mental Developmental Index (MDI ) <70; ②Psychiatric Motor Development Index (PDI) <70; ③Lack or presence of cerebral palsy; ④The birth weight is less than the 10th percentile by age. Logistic regression models were used to predict the likely outcome of these children without follow-up evaluations, and the predicted distribution probabilities were used for group comparisons. Results: Children who were followed up were more likely to be one of many births than those who lost their follow-up, who had received postnatal glucocorticoid and had