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胆管癌是胆管上皮细胞分化异常的肝胆管肿瘤，根据解剖位置可分为肝内胆管癌（ iCCA）、肝门部胆管癌（ PCCA）、远端胆管癌。因胆管癌的位置特别、患者早期临床特征不明显，所以早期确诊较为困难。胆管癌的确诊需要高度特异性指标与临床、内镜、影像学检查等相结合。iCCA通常采取外科治疗，而对部分PCCA可以选择新铺助放化疗后肝移植治疗。“,”Cholangiocarcinoma( CCA) is a bile duct tumor with bile duct epithelial cell disdifferentia-tion.According to anatomical location,it can be divided into intrahepatic biliary cancer,perihilar cholangio-carcinoma and distal cholangiocarcinoma .Because of its special anatomic location and silent clinical feature , it is difficult to be diagnosed at early stage .Cholangiocarcinoma′diagnosis requires indexes of high degree of specificity and multidisciplinary approaches including clinical,endoscopic, and radiographic examination. Patients with intrahepatic cholangiocarcinoma usually take surgical treatment , but patients with perihilar cholangiocarcinoma can select liver transplantation after neoadjuvant chemoradiation .