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目的:探讨妊娠合并血小板减少症的病因和围生理期处理方法。方法:回顾分析56例妊娠合并血小板减少患者临床资料根据患者血小板计数分为三组,妊娠早、中期发现血小板减少患者,给予口服药物,低于20×109/L时给予糖皮质激素、丙种球蛋白和/或输注血小板等提高血小板计数,终止妊娠。结果:56例妊娠合并血小板减少的病因为妊娠期血小板减少症38例,特发性血小板减少症13例,妊高征3例,再障1例,原因不明1例。阴道分娩35例,剖宫产21例,均有产科指征,产后出血8例,活产新生儿56例。结论:妊娠合并血小板减少症是产科常见出血疾病,产前适当提高血小板计数可以减少并发症的发生,保障围产期母婴健康。
Objective: To investigate the etiology and management of thrombocytopenia in pregnancy. Methods: The clinical data of 56 cases of pregnancy with thrombocytopenia were retrospectively analyzed. The patients were divided into three groups according to their platelet count. Patients with thrombocytopenia were found in the early and middle third trimester of pregnancy. Oral drugs were given. When the concentration was below 20 × 109 / L, glucocorticoid, Protein and / or platelet transfusion increased platelet count, termination of pregnancy. Results: The causes of 56 cases of pregnancy with thrombocytopenia were 38 cases of thrombocytopenia in pregnancy, 13 cases of idiopathic thrombocytopenia, 3 cases of pregnancy induced hypertension and 1 case of aplastic anemia. The cause of unknown thrombosis was 1 case. 35 cases of vaginal delivery, 21 cases of cesarean section, obstetric indications, postpartum hemorrhage in 8 cases, 56 live births in newborns. Conclusion: Pregnancy with thrombocytopenia is a common obstetric hemorrhagic disease, prenatal appropriate increase in platelet count can reduce the incidence of complications, to protect perinatal maternal and infant health.