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特发性或周期性水肿几乎是妇女的一种特殊病症。特点为间歇性发作,因站立而加重。诊断该病首先应排除其他原因的水肿,以及白日体重明显增加的表现。病因目前尚不清楚,曾有研究指出:周期性水肿妇女有慢性低血容量而在站立时引起尿量和钠的排出减少,但对低血容量的机理尚有争论。还注意到周期性水肿妇女显示的情绪不稳定,严重的抑郁症常与下丘脑-垂体轴障碍有关。因此作者对14例患者进行了促甲状腺释放激素(TRH)和黄体生成激素释放激素(LHRH)试验研究下丘脑功能。14例为主诉周身水肿白日体重增加超过1.40kg,经体检及生化测定排除了引起水肿的其他原因,病人平均年龄35±SEM3.0岁,平均体重67±3.5kg,均无服避孕药史,但有11例用过利尿剂,其中8例于3个月前停服,3例继续服用。正常妇女6例作对照,平均年龄为32±2.5岁,平均体重
Idiopathic or periodic edema is almost a woman’s special condition. Characteristics of intermittent attacks, due to standing and aggravating. The diagnosis of the disease should first rule out other causes of edema, as well as significantly increased daytime body weight performance. Etiology is not clear, studies have pointed out: cyclical edema in women with chronic hypovolemia caused by standing urine and sodium excretion decreased, but the mechanism of hypovolemia is still controversial. Also noted that women with cyclical edema showed emotional instability, severe depression often associated with hypothalamic-pituitary axis disorders. Therefore, the authors studied hypothalamic function in 14 patients with thyroid-releasing hormone (TRH) and luteinizing hormone releasing hormone (LHRH). 14 cases of the main complaint of whole body edema body weight gain over 1.40kg, physical examination and biochemical tests to exclude other causes of edema, the average age of patients 35 ± SEM3.0 years old, average body weight 67 ± 3.5kg, were no history of contraceptives However, diuretics were used in 11 cases, of which 8 were discontinued 3 months ago and 3 were continued. Six normal women as a control, the average age of 32 ± 2.5 years, the average body weight