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为研究骨组织工程材料的成形性,基于低温沉积制造工艺,研究了PLGA/TCP配制成浆料的温度、黏度、成形性之间的关系。探讨了材料的黏度随温度的变化关系,通过对不同温度的材料进行成形试验,表明材料的黏度对宏观成形效果起着决定性的作用,而温度变化使试样的宏观和微观结构具有较大差异。因此要实现宏观上的结构和外形的精确成形,必须要保证材料的黏度。对于孔隙率、微孔大小等微观结构的不同要求,可以通过改变温度参数即黏度来适应成形性的要求。
In order to study the formability of bone tissue engineered materials, the relationship between temperature, viscosity and formability of PLGA / TCP slurry was studied based on low temperature deposition process. The relationship between the viscosity and the temperature was discussed. Through the forming tests on the materials with different temperatures, the viscosity of the materials played a decisive role in the macroscopic forming effect. However, the changes of the macrostructures and microstructures of the samples were quite different . Therefore, macroscopic structure and shape to achieve the exact shape, we must ensure that the viscosity of the material. For porosity, pore size and other microstructural different requirements, you can change the temperature parameters that viscosity to meet the requirements of formability.