典型的Graves病具有特征性的症状和体征,故较易诊断。但临床上不典型病例并非罕见,常给诊断和治疗带来困难。本文就Graves病的边缘性疾病、且与桥本氏病有关的所谓桥本氏毒症(Hashitoxicosis)和表现有甲状腺毒症之桥本氏病的概念、诊断和治疗进行讨论。 桥本氏毒症 一、概念:Hashitoxicosis一词系Ha-shimoto和thyrotoxicosis二词的合成,但其概念尚未完全统一。此词最早由Doniach创用,DeGroot最早用来记载伴突眼的活动 Typical Graves disease has characteristic symptoms and signs, it is easier to diagnose. However, atypical cases of clinical is not uncommon, often to the diagnosis and treatment difficulties. This article discusses the concept, diagnosis and treatment of the borderline disease of Graves’ disease, and the so-called Hashitoxicosis associated with Hashimoto’s disease and Hashimoto’s disease with thyrotoxicosis. Hashimoto’s disease I. Concept: The word Hashitoxicosis is a combination of the words Ha-shimoto and thyrotoxicosis, but its concept has not yet been completely unified. The term was first used by Doniach, DeGroot earliest used to record the activity with the exophthalmus