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目的:研究不孕妇女支原体(ureaplasmaurealyticum,UU)、衣原体(chlamydiatranydia,CT)感染与抗精子抗体(antispermantibody,ASA)之间的相互关系。方法:选择不孕妇女286例,其中原发不孕86例,继发不孕200例;并选择健康已孕妇女100例作为对照组。通过支原体培养法和衣原体一步免疫层析法检测UU、CT感染,应用酶联免疫吸附法检测血清中ASA。结果:不孕组UU、CT感染率、ASA阳性率明显高于对照组,差异均有显著性(P<0.05);不孕组中ASA阳性患者UU、CT感染率较阴性患者高,差异有显著性(P<0.05);继发不孕患者UU、CT感染率高于原发不孕患者,差异有显著性(P<0.05)。结论:UU、CT感染及ASA均可造成女性不孕,ASA的产生与UU、CT感染有关,继发不孕与UU、CT感染有关。
Objective: To study the relationship between ureaplasma urealyticum (UU), chlamydiatranydia (CT) infection and antispermmantibody (ASA) in infertile women. Methods: 286 infertile women were selected, including 86 cases of primary infertility and 200 cases of secondary infertility. 100 healthy pregnant women were selected as the control group. UU and CT were detected by mycoplasma culture and Chlamydia immunochromatography, and serum ASA was detected by enzyme-linked immunosorbent assay. Results: The positive rates of UU, CT and ASA in infertility group were significantly higher than those in control group (P <0.05). The prevalence of UU and CT in infertile group was higher than that in negative group (P <0.05). The prevalence of UU and CT in secondary infertility patients was higher than that in primary infertility patients (P <0.05). CONCLUSION: UU, CT and ASA can cause female infertility. The production of ASA is related to UU and CT infection. Secondary infertility is associated with UU and CT infection.