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用甲基纤维素半固体培养法，观察了黄芪多糖对小鼠骨髓巨核系祖细胞（ＣＦＵ－ＭＫ）生成的影响。结果显示，浓度２５ｍｇ／Ｌ的黄芪多糖在体外能刺能激小鼠ＣＦＵ－ＭＫ的生成；２０ｍｇ／ｋｇ和１００ｍｇ／ｋｇ的黄芪多糖连续注射３ｄ，小鼠ＣＦＵ－ＭＫ的生成量均明显高于对照组；对环磷酰胺（ＣＴＸ）引起的小鼠ＣＦＵ－ＭＫ生成下降，黄芪多糖无保护作用。提示黄芪多糖对小鼠ＣＦＵ－ＭＫ的生成有促进作用，但无法缓解ＣＴＸ对小鼠ＣＦＵ－ＭＫ生成的抑制作用
The effects of astragalus polysaccharide on the generation of murine bone marrow megakaryocyte progenitor cells (CFU-MK) were observed using methylcellulose semi-solid culture. The results showed that astragalus polysaccharides with a concentration of 25mg / L stimulated the formation of CFU-MK in mice in vitro. Astragalus polysaccharide at 20mg / kg and 100mg / kg produced a significant increase in CFU-MK production Control group; Cyclophosphamide (CTX) -induced CFU-MK production in mice decreased, APS no protective effect. It suggested that APS could promote CFU-MK production in mice, but could not alleviate the inhibitory effect of CTX on CFU-MK production in mice