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癌胚抗原(Carcinoembryonic antigen,CEA)是胚胎基因的产物之一。首先由Gold和Fredman于1965年从结肠腺癌和胎儿结肠粘膜组织浸液中分离出来。开始认为仅是消化道癌肿的标记。近20年的研究发现,CEA存在于各种肿瘤、器官和体液中。一、CEA的理化免疫学性质 CEA是大分子糖蛋白,高度提纯的CEA表现相当程度的分子间和分子内的异质性,可能与其
Carcinoembryonic antigen (CEA) is one of the products of embryonic gene. First by Gold and Fredman in 1965 from colon adenocarcinoma and fetal colonic mucosal tissue immersion isolated. Began to think that only the signs of gastrointestinal cancer. Nearly 20 years of research found that CEA exists in a variety of tumors, organs and body fluids. First, the CEA physio-chemical immunology CEA is a macromolecular glycoprotein, highly purified CEA showed considerable degree of inter-molecular and intramolecular heterogeneity, and its possible