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本文介绍了重组人白细胞介素4(rhu IL-4)一级结构及高级结构;通过rhu IL-4与单克隆抗体相互作用,初步探讨了其结构与功能的关系;并将rhu IL-4与同一受体超家族中其它细胞因子和激素的三级结构作了比较。
In this paper, the primary structure and the higher structure of recombinant human interleukin 4 (rhu IL-4) were introduced. The relationship between the structure and function of rhu IL-4 was discussed through the interaction between rhu IL-4 and the monoclonal antibody. The tertiary structure of other cytokines and hormones in the same receptor superfamily was compared.