Purposes: To compare the multi-channel pattern visual evoked potentials to Humphrey perimetry in the assessment of central visual function in primary open angle glaucoma. Methods: The multi-channel checkerboard reversal PVEPs waves to full-field and half-field stimulus of 25 normal persons and 74 patients with primary open angle glaucoma were recorded and analyzed, All patients were examined using Humphrey Field Analyzer. The area of visual field corresponding to the area of retina stimulated during multi-channel PVEPs testing were analysed, straight-line correlation and regression analyses of the various multi-channel PVEPs parameters and the total dB losses were performed.Results: The multi-channel PVEPs demonstrated a low detection rate compared with Humprey perimetry in the early glaucoma, absolute latency and field loss were correlated in the late stage of glaucoma, and absolute amplitude and field loss were not correlated. Conclusions: In relation to signalling early loss the multi-channel PVEPs w Purposes: To compare the multi-channel pattern visual evoked potentials to Humphrey perimetry in the assessment of central visual function in primary open angle glaucoma. Methods: The multi-channel checkerboard reversal PVEPs waves to full-field and half-field stimulus of 25 normal persons and 74 patients with primary open angle glaucoma were recorded and analyzed, All patients were examined using Humphrey Field Analyzer. The area of ​​visual field corresponding to the area of ​​retina stimulated during multi-channel PVEPs testing were analyzed, straight-line correlation and regression analyzes of the various multi-channel PVEPs parameters and the total dB losses were performed. Results: The multi-channel PVEPs demonstrated a low detection rate compared with Humprey perimetry in the early glaucoma, absolute latency and field loss were correlated in the late stage of glaucoma, and absolute amplitude and field loss were not correlated. Conclusions: In relation to signaling early loss the mul ti-channel PVEPs w